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Frequencies are defined as: Very common (≥1/10); common (≥1/100, <1/10); uncommon (≥1/1000, <1/100); rare (≥1/10,000, <1/1000) or very rare (<1/10,000); not known (cannot be estimated from the available data).
Nervous System Disorders: Very common: Headache. Common: Dizziness, somnolence.
Cardiac Disorders: Common: Tachycardia. Uncommon: Aggravated angina pectoris.
Vascular Disorders: Common: Orthostatic hypotension. Uncommon: Circulatory collapse (sometimes accompanied by bradyarrhythmia and syncope). Not known: Hypotension.
Gastrointestinal Disorders: Uncommon: Nausea, vomiting, heartburn. Very rare: Heartburn.
Skin and Subcutaneous Tissue Disorders: Uncommon: Allergic skin reactions (eg, rash), flushing. Very rare: Angioedema, Stevens-Johnson syndrome. Not known: Exfoliative dermatitis.
General Disorders and Administration Site Conditions: Common: Asthenia.
Severe hypotensive responses have been reported for organic nitrates including nausea, vomiting, restlessness, pallor, and excessive perspiration.
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